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Volume 3 Issue 3
Jul.  2023
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Article Navigation >  Frigid Zone Medicine  > 2023  >  3(3): 134-160
Weijie Guan, Jianxing He. Clinical characteristics, management, and prevention of coronavirus disease 2019[J]. Frigid Zone Medicine, 2023, 3(3): 134-160. doi: 10.2478/fzm-2023-0019
Citation: Weijie Guan, Jianxing He. Clinical characteristics, management, and prevention of coronavirus disease 2019[J]. Frigid Zone Medicine, 2023, 3(3): 134-160. doi: 10.2478/fzm-2023-0019
shu

Clinical characteristics, management, and prevention of coronavirus disease 2019

doi: 10.2478/fzm-2023-0019
  • 1.

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China

  • 2.

    Department of Thoracic Surgery, Guangzhou Institute for Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China

  • 3.

    Department of Respiratory and Critical Care Medicine, Foshan Second People's Hospital, Affiliated Foshan Hospital of Southern Medical University, Foshan 528000, China

Funds:

the National Science Foundation - Outstanding Youth Fund 82222001

the Emergency Key Program of Guangzhou Laboratory EKPG22-02

the Guangzhou Institute for Respiratory Health Open Project (funded by China Evergrande Group) 2020GIRHHMS09

the Guangzhou Institute for Respiratory Health Open Project (funded by China Evergrande Group) 2020GIRHHMS19

the Zhongnanshan Medical Foundation of Guangdong Province funding number not applicable

the Penghua Care Fund to the Medical Pioneers against Covid-19 of Shenzhen Social Commonweal Foundation funding number not applicable, Guan W J

More Information
  • Corresponding author: Jianxing He, E-mail address: hejx@vip.163.com
  • Received Date: 2022-05-26
  • Accepted Date: 2023-02-09
    • Available Online: 2023-07-25
    Abstract
  • Coronavirus disease 2019 (COVID-19) is the third severe acute respiratory disease of the 21st century and the most aggressive global pandemic to date. The whole population has been susceptible to the disease, particularly the emerging variants of the virus. The core pathophysiological mechanism is viral sepsis that can lead to the respiratory tract disorders and even systemic disorders such as cytokine release syndrome, thrombosis, abnormal angiogenesis, and multiple organ dysfunction. Despite only few licensed treatments to date, rapid advances have been made in exploring the effectiveness and safety of pharmacological interventions and vaccines. However, three pillars of preventative and control measures - proactive contact tracing, wearing facial masks, and social distancing - are essential to combat the ongoing pandemic. As the number of patients recovering from COVID-19 rapidly increases, the world has entered the era of caring for patients during the convalescence phase. This phase still represents a largely unmet medical need globally.

     

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