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Volume 2 Issue 4
Oct.  2022
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Article Navigation >  Frigid Zone Medicine  > 2022  >  2(4): 251-256
Zhidan Sun, Yan Hou, Zheng Zhang, Benzhi Cai, Jinliang Li. Electrocardiogram abnormalities and higher body mass index as clinically applicable factors for predicting poor outcome in patients with coronavirus disease 2019[J]. Frigid Zone Medicine, 2022, 2(4): 251-256. doi: 10.2478/fzm-2022-0032
Citation: Zhidan Sun, Yan Hou, Zheng Zhang, Benzhi Cai, Jinliang Li. Electrocardiogram abnormalities and higher body mass index as clinically applicable factors for predicting poor outcome in patients with coronavirus disease 2019[J]. Frigid Zone Medicine, 2022, 2(4): 251-256. doi: 10.2478/fzm-2022-0032
shu

Electrocardiogram abnormalities and higher body mass index as clinically applicable factors for predicting poor outcome in patients with coronavirus disease 2019

doi: 10.2478/fzm-2022-0032
  • 1.

    Department of Pharmacy, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China

  • 2.

    Department of Epidemiology and Biostatistics, Public Health School, Harbin Medical University, Harbin 150081, China

  • 3.

    Department of Critical Care Medicine, Harbin Infectious Disease Hospital, Harbin 150030, China

  • 4.

    Department of Cardiology, Harbin Infectious Disease Hospital, Harbin 150030, China

More Information
  • Corresponding author: Benzhi Cai, E-mail: caibenzhi@163.com; Jinliang Li, E-mail: ccworkshop@126.com
  • Received Date: 2021-12-20
  • Accepted Date: 2022-09-02
    • Available Online: 2022-10-30
    Abstract
  •   Background  Patients with coronavirus disease 2019 (COVID-19) have high resource utilization. Identifying the causes of severe COVID-19 is helpful for early intervention to reduce the consumption of medical resources.  Methods  We included 103 patients with COVID-19 in this single-center observational study. To evaluate the incidence, predictors, and effects of COVID-19, we analyzed demographic information, laboratory results, comorbidities, and vital signs as factors for association with severe COVID-19.  Results  The incidence of severe COVID-19 was 16.5% and the percent poor outcome (including mortality, entering in ICU or transferred to a superior hospital) was 6.8%. The majority of severe COVID-19 patients had abnormal electrocardiogram (ECG) (82.35%), hypertension (76.47%) and other cardiac diseases (58.82%). Multivariate logistic regression was used to determine the predictors of severe illness. Abnormal body mass index (BMI) and ECG (P < 0.05) were independent predictors of severe COVID-19. ECG abnormality was associated with increased odds of poor outcome (area under the receiver operating characteristic curves [AUC], 0.793; P = 0.010) and severe COVID-19 (AUC, 0.807; P < 0.0001). Overweight was also associated with increased odds of poor outcome (AUC, 0.728; P = 0.045) and severe illness COVID-19 (AUC, 0.816; P < 0.0001).  Conclusion  Overweight and electrophysiological disorders on admission are important predictors of prognosis of patients with COVID-19.

     

    • Authors' contributions
    Cai B and Li J generated the idea for and designed the study and had full access to all data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Sun Z and Hou Y contributed to writing of the report and the statistical analysis. All authors contributed to data acquisition, data analysis, or data interpretation, and reviewed and approved the final version.
    Ethical approval and consent to participate
    This clinical study was approved by the Ethics Commission of Harbin Infectious Disease Hospital (2020 No.20). Written informed consent for the study was obtained from all participants.
    Conflicts of interests
    All authors declare no competing interests.
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