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Volume 3 Issue 3
Jul.  2023
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Article Navigation >  Frigid Zone Medicine  > 2023  >  3(3): 167-175
Guoqing Zhang, Cuiqing Liu, Qinghua Sun. The impact of low ambient temperature on cardiovascular health[J]. Frigid Zone Medicine, 2023, 3(3): 167-175. doi: 10.2478/fzm-2023-0021
Citation: Guoqing Zhang, Cuiqing Liu, Qinghua Sun. The impact of low ambient temperature on cardiovascular health[J]. Frigid Zone Medicine, 2023, 3(3): 167-175. doi: 10.2478/fzm-2023-0021
shu

The impact of low ambient temperature on cardiovascular health

doi: 10.2478/fzm-2023-0021
  • 1.

    School of Public Health and Joint China-US Research Center for Environment and Pulmonary Diseases, Zhejiang Chinese Medical University, Hangzhou 310053, China

  • 2.

    Zhejiang International Science and Technology Cooperation Base of Air Pollution and Health, Hangzhou 310053, China

More Information
  • Corresponding author: Cuiqing Liu, E-mail address: liucuiqing@zcmu.edu.cn; Qinghua Sun, E-mail address: qhsun@zcmu.edu.cn
  • Received Date: 2022-06-13
  • Accepted Date: 2023-04-12
    • Available Online: 2023-07-25
    Abstract
  • Extreme weather events and climate change have witnessed a substantial increase in recent years, leading to heightened concerns. The rise in abnormal ambient temperatures, both in intensity and frequency, directly and indirectly impacts cardiovascular health. While the impact of high ambient temperatures on cardiovascular response is a common concern in the context of global warming, the significance of low temperatures cannot be overlooked. The challenges posed by low temperatures contribute to increased cardiovascular morbidity and mortality, posing a significant threat to global public health. This review aims to provide an overview of the relationship between low ambient temperature and cardiovascular health, encompassing the burden of cardiovascular outcomes and underlying mechanisms. Additionally, the review explores strategies for cold adaptation and cardioprotection. We posit that to optimize cold adaptation strategies, future research should delve deeper into the underlying mechanisms of cardiovascular health in response to low ambient temperature exposure.

     

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  • [1]
    Romanello M, McGushin A, Di Napoli C, et al. The 2021 report of the Lancet Countdown on health and climate change: code red for a healthy future. Lancet, 2021; 398(10311): 1619–1662. doi: 10.1016/S0140-6736(21)01787-6
    [2]
    Cai W, Zhang C, Zhang S, et al. The 2021 China report of the Lancet Countdown on health and climate change: seizing the window of opportunity. Lancet Public Health, 2021; 6(12): e932–e947. doi: 10.1016/S2468-2667(21)00209-7
    [3]
    Romanello M, van Daalen K, Anto J M, et al. Tracking progress on health and climate change in Europe. Lancet Public Health, 2021; 6(11): e858–e865. doi: 10.1016/S2468-2667(21)00207-3
    [4]
    Watts N, Amann M, Arnell N, et al. The 2020 report of The Lancet Countdown on health and climate change: responding to converging crises. Lancet, 2021; 397(10269): 129–170. doi: 10.1016/S0140-6736(20)32290-X
    [5]
    Ebi K L, Vanos J, Baldwin J W, et al. Extreme weather and climate change: Population health and health system implications. Annu Rev Public Health, 2021; 42: 293–315. doi: 10.1146/annurev-publhealth-012420-105026
    [6]
    Kotcher J, Maibach E, Miller J, et al. Views of health professionals on climate change and health: a multinational survey study. Lancet Planet Health, 2021; 5(5): e316–e323. doi: 10.1016/S2542-5196(21)00053-X
    [7]
    Johnson N C, Xie S P, Kosaka Y, et al. Increasing occurrence of cold and warm extremes during the recent global warming slowdown. Nat Commun, 2018; 9(1): 1724. doi: 10.1038/s41467-018-04040-y
    [8]
    Wang C, Yao Y, Wang H, et al. The 2020 summer floods and 2020/21 winter extreme cold surges in China and the 2020 typhoon season in the Western North Pacific. Adv Atmos Sci, 2021; 38(6): 896–904. doi: 10.1007/s00376-021-1094-y
    [9]
    He Q, Silliman B R. Climate change, human impacts, and coastal ecosystems in the anthropocene. Curr Biol, 2019; 29(19): R1021–R1035. doi: 10.1016/j.cub.2019.08.042
    [10]
    Song X, Wang S, Hu Y, et al. Impact of ambient temperature on morbidity and mortality: An overview of reviews. Sci Total Environ, 2017; 586: 241–254. doi: 10.1016/j.scitotenv.2017.01.212
    [11]
    Argacha J F, Bourdrel T, van de Borne P. Ecology of the cardiovascular system: A focus on air-related environmental factors. Trends Cardiovasc Med, 2018; 28(2): 112–126. doi: 10.1016/j.tcm.2017.07.013
    [12]
    Liu C Q, Yavar Z B, Sun Q H. Cardiovascular response to thermoregulatory challenges. Am J Physiol Heart Circ Physiol, 2015; 309(11): H1793–H1812. doi: 10.1152/ajpheart.00199.2015
    [13]
    Chen J M, Gao Y, Jiang Y X, et al. Low ambient temperature and temperature drop between neighbouring days and acute aortic dissection: a case-crossover study. European Heart Journal, 2022; 43(3): 228–235. doi: 10.1093/eurheartj/ehab803
    [14]
    Ciuha U, Sotiridis A, Mlinar T, et al. Heat acclimation enhances the cold-induced vasodilation response. Eur J Appl Physiol, 2021; 121(11): 3005–3015. doi: 10.1007/s00421-021-04761-x
    [15]
    Chen C W, Wu C H, Liou Y S, et al. Roles of cardiovascular autonomic regulation and sleep patterns in high blood pressure induced by mild cold exposure in rats. Hypertens Res, 2021; 44(6): 662–673. doi: 10.1038/s41440-021-00619-z
    [16]
    Umishio W, Ikaga T, Kario K, et al. Electrocardiogram abnormalities in residents in cold homes: a cross-sectional analysis of the nationwide Smart Wellness Housing survey in Japan. Environ Health Prev Med, 2021; 26(1): 104. doi: 10.1186/s12199-021-01024-1
    [17]
    Bai L, Cirendunzhu, Woodward A, et al. Temperature and mortality on the roof of the world: a time-series analysis in three Tibetan counties, China. Sci Total Environ, 2014; 485–486: 41–48.
    [18]
    Wang B, Chai G R, Sha Y Z, et al. Association between ambient temperature and cardiovascular disease hospitalisations among farmers in suburban northwest China. Int J Biometeorol, 2022; 66(7): 1317–1327. doi: 10.1007/s00484-022-02278-2
    [19]
    Lv L S, Zhou C L, Jin D H, et al. Impact of ambient temperature on life loss per death from cardiovascular diseases: a multicenter study in central China. Environ Sci Pollut Res Int, 2022; 29(11): 15791–15799. doi: 10.1007/s11356-021-16888-7
    [20]
    Xu R, Shi C, Wei J, et al. Cause-specific cardiovascular disease mortality attributable to ambient temperature: A time-stratified case-crossover study in Jiangsu province, China. Ecotoxicol Environ Saf, 2022; 236: 113498. doi: 10.1016/j.ecoenv.2022.113498
    [21]
    Fonseca-Rodriguez O, Sheridan S C, Lundevaller E H, et al. Effect of extreme hot and cold weather on cause-specific hospitalizations in Sweden: A time series analysis. Environ Res, 2021; 193: 110535. doi: 10.1016/j.envres.2020.110535
    [22]
    Wang Q, Li C, Guo Y, et al. Environmental ambient temperature and blood pressure in adults: A systematic review and meta-analysis. Sci Total Environ; 2017; 575: 276–286. doi: 10.1016/j.scitotenv.2016.10.019
    [23]
    Chen R J, Yin P, Wang L J, et al. Association between ambient temperature and mortality risk and burden: time series study in 272 main Chinese cities. BMJ, 2018; 363: k4306.
    [24]
    Denpetkul T, Phosri A. Daily ambient temperature and mortality in Thailand: Estimated effects, attributable risks, and effect modifications by greenness. Sci Total Environ. 2021; 791: 148373. doi: 10.1016/j.scitotenv.2021.148373
    [25]
    Lin Y K, Sung F C, Honda Y, et al. Comparative assessments of mortality from and morbidity of circulatory diseases in association with extreme temperatures. Sci Total Environ, 2020; 723: 138012. doi: 10.1016/j.scitotenv.2020.138012
    [26]
    Hu J, Hou Z, Xu Y, et al. Life loss of cardiovascular diseases per death attributable to ambient temperature: A national time series analysis based on 364 locations in China. Sci Total Environ, 2021; 756: 142614. doi: 10.1016/j.scitotenv.2020.142614
    [27]
    Zhang H, Wang Q, Zhang Y, et al. Modeling the impacts of ambient temperatures on cardiovascular mortality in Yinchuan: evidence from a northwestern city of China. Environ Sci Pollut Res Int, 2018; 25(6): 6036–6043. doi: 10.1007/s11356-017-0920-3
    [28]
    Hurtado-Diaz M, Cruz J C, Texcalac-Sangrador J L, et al. Short-term effects of ambient temperature on non-external and cardiovascular mortality among older adults of metropolitan areas of Mexico. Int J Biometeorol, 2019; 63(12): 1641–1650. doi: 10.1007/s00484-019-01778-y
    [29]
    Bai L, Li Q, Wang J, et al. Increased coronary heart disease and stroke hospitalisations from ambient temperatures in Ontario. Heart, 2018; 104(8): 673–679. doi: 10.1136/heartjnl-2017-311821
    [30]
    Macintyre H L, Heaviside C, Cai X M, et al. The winter urban heat island: Impacts on cold-related mortality in a highly urbanized European region for present and future climate. Environ Int, 2021; 154: 106530. doi: 10.1016/j.envint.2021.106530
    [31]
    Xu E, Li Y N, Li T T, et al. Association between ambient temperature and ambulance dispatch: a systematic review and meta-analysis. Environ Sci Pollut Res Int, 2022; 29(44): 66335–66347. doi: 10.1007/s11356-022-20508-3
    [32]
    Bai L, Li Q, Wang J, et al. Hospitalizations from hypertensive diseases, diabetes, and arrhythmia in relation to low and high temperatures: Population-based study. Sci Rep, 2016; 6: 30283. doi: 10.1038/srep30283
    [33]
    Hensel M, Stuhr M, Geppert D, et al. Relationship between ambient temperature and frequency and severity of cardiovascular emergencies: A prospective observational study based on out-of-hospital care data. Int J Cardiol, 2017; 228: 553–557. doi: 10.1016/j.ijcard.2016.11.155
    [34]
    Yang J, Yin P, Zhou M, et al. Cardiovascular mortality risk attributable to ambient temperature in China. Heart, 2015; 101(24): 1966–1972. doi: 10.1136/heartjnl-2015-308062
    [35]
    Luo Q L, Li S S, Guo Y M, et al. A systematic review and meta-analysis of the association between daily mean temperature and mortality in China. Environ Res, 2019; 173: 281–299. doi: 10.1016/j.envres.2019.03.044
    [36]
    Wichmann J, Andersen Z, Ketzel M, et al. Apparent temperature and cause-specific emergency hospital admissions in Greater Copenhagen, Denmark. PLoS One, 2011; 6(7): e22904. doi: 10.1371/journal.pone.0022904
    [37]
    Phung D, Thai P K, Guo Y, et al. Ambient temperature and risk of cardiovascular hospitalization: An updated systematic review and meta-analysis. Sci Total Environ, 2016; 550: 1084–1102. doi: 10.1016/j.scitotenv.2016.01.154
    [38]
    Fu S H, Gasparrini A, Rodriguez P S, et al. Mortality attributable to hot and cold ambient temperatures in India: a nationally representative case-crossover study. PLoS Med, 2018; 15(7): e1002619. doi: 10.1371/journal.pmed.1002619
    [39]
    Tian L W, Qiu H, Sun S Z, et al. Emergency cardiovascular hospitalization risk attributable to cold temperatures in Hong Kong. Circ Cardiovasc Qual Outcomes, 2016; 9(2): 135–142. doi: 10.1161/CIRCOUTCOMES.115.002410
    [40]
    Zhao Q, Zhao Y, Li S, et al. Impact of ambient temperature on clinical visits for cardio-respiratory diseases in rural villages in northwest China. Sci Total Environ, 2018; 612: 379–385. doi: 10.1016/j.scitotenv.2017.08.244
    [41]
    Cheng J, Ho H C, Su H, et al. Low ambient temperature shortened life expectancy in Hong Kong: A time-series analysis of 1.4 million years of life lost from cardiorespiratory diseases. Environ Res, 2021; 201: 111652. doi: 10.1016/j.envres.2021.111652
    [42]
    Li H, Yao Y, Duan Y, et al. Years of life lost and mortality risk attributable to non-optimum temperature in Shenzhen: a time-series study. J Expo Sci Environ Epidemiol, 2021; 31(1): 187–196. doi: 10.1038/s41370-020-0202-x
    [43]
    Lv L S, Jin D H, Ma W J, et al. The impact of non-optimum ambient temperature on years of life lost: A multi-county observational study in Hunan, China. Int J Environ Res Public Health, 2020; 17(11): 3810. doi: 10.3390/ijerph17113810
    [44]
    Liu T, Zhou C, Zhang H, et al. Ambient temperature and years of life lost: A national study in China. Innovation (Camb), 2021; 2(1): 100072.
    [45]
    Luan G, Yin P, Li T, et al. The years of life lost on cardiovascular disease attributable to ambient temperature in China. Sci Rep, 2017; 7(1): 13531. doi: 10.1038/s41598-017-13225-2
    [46]
    Zhang Y Q, Li C L, Feng R J, et al. The short-term effect of ambient temperature on mortality in Wuhan, China: A time-series study using a distributed lag non-linear model. Int J Environ Res Public Health, 2016; 13(7): 722. doi: 10.3390/ijerph13070722
    [47]
    Carder M, McNamee R, Beverland I, et al. The lagged effect of cold temperature and wind chill on cardiorespiratory mortality in Scotland. Occup Environ Med, 2005; 62(10): 702–710. doi: 10.1136/oem.2004.016394
    [48]
    Wang X, Li G, Liu L, et al. Effects of extreme temperatures on cause-specific cardiovascular mortality in China. Int J Environ Res Public Health, 2015; 12(12): 16136–16156. doi: 10.3390/ijerph121215042
    [49]
    Zeka A, Browne S, McAvoy H, et al. The association of cold weather and all-cause and cause-specific mortality in the island of Ireland between 1984 and 2007. Environ Health, 2014; 13: 104. doi: 10.1186/1476-069X-13-104
    [50]
    Bunker A, Wildenhain J, Vandenbergh A, et al. Effects of air temperature on climate-sensitive mortality and morbidity outcomes in the elderly; A systematic review and meta-analysis of epidemiological evidence. EBioMedicine, 2016; 6: 258–268. doi: 10.1016/j.ebiom.2016.02.034
    [51]
    Liu X L, Kong D H, Fu J, et al. Association between extreme temperature and acute myocardial infarction hospital admissions in Beijing, China: 2013–2016. Plos One, 2018; 13(10): e0204706. doi: 10.1371/journal.pone.0204706
    [52]
    Kang Y, Han Y, Guan T, et al. Clinical blood pressure responses to daily ambient temperature exposure in China: An analysis based on a representative nationwide population. Sci Total Environ, 2020; 705: 135762. doi: 10.1016/j.scitotenv.2019.135762
    [53]
    Mohammadi R, Soori H, Alipour A, et al. The impact of ambient temperature on acute myocardial infarction admissions in Tehran, Iran. J Therm Biol, 2018; 73: 24–31. doi: 10.1016/j.jtherbio.2018.02.008
    [54]
    Cui L, Geng X, Ding T, et al. Impact of ambient temperature on hospital admissions for cardiovascular disease in Hefei City, China. Int J Biometeorol, 2019; 63(6): 723–734. doi: 10.1007/s00484-019-01687-0
    [55]
    Sartini C, Barry S J E, Wannamethee S G, et al. Effect of cold spells and their modifiers on cardiovascular disease events: Evidence from two prospective studies. Int J Cardiol, 2016; 218: 275–283. doi: 10.1016/j.ijcard.2016.05.012
    [56]
    Xu D, Zhang Y, Wang B, et al. Acute effects of temperature exposure on blood pressure: An hourly level panel study. Environ Int, 2019; 124: 493–500. doi: 10.1016/j.envint.2019.01.045
    [57]
    Masajtis-Zagajewska A, Pawlowicz E, Nowicki M. Effect of short-term cold exposure on central aortic blood pressure in patients with CKD. Nephron, 2021; 145(1): 20–26. doi: 10.1159/000510365
    [58]
    Lavigne E, Gasparrini A, Wang X, et al. Extreme ambient temperatures and cardiorespiratory emergency room visits: assessing risk by comorbid health conditions in a time series study. Environ Health, 2014; 13(1): 5. doi: 10.1186/1476-069X-13-5
    [59]
    Ponjoan A, Blanch J, Alves-Cabratosa L, et al. Effects of extreme temperatures on cardiovascular emergency hospitalizations in a Mediterranean region: a self-controlled case series study. Environ Health, 2017; 16(1): 32. doi: 10.1186/s12940-017-0238-0
    [60]
    Zhang J, Chen R, Zhang G, et al. PM2.5 increases mouse blood pressure by activating toll-like receptor 3. Ecotoxicol Environ Saf, 2022; 234: 113368. doi: 10.1016/j.ecoenv.2022.113368
    [61]
    Kim S R, Choi S, Kim K, et al. Association of the combined effects of air pollution and changes in physical activity with cardiovascular disease in young adults. Eur Heart J, 2021; 42(25): 2487–2497. doi: 10.1093/eurheartj/ehab139
    [62]
    Klompmaker J O, Hart J E, James P, et al. Air pollution and cardiovascular disease hospitalization - Are associations modified by greenness, temperature and humidity? Environ Int, 2021; 156: 106715. doi: 10.1016/j.envint.2021.106715
    [63]
    Hsu W H, Hwang S A, Kinney P L, et al. Seasonal and temperature modifications of the association between fine particulate air pollution and cardiovascular hospitalization in New York state. Sci Total Environ, 2017; 578: 626–632. doi: 10.1016/j.scitotenv.2016.11.008
    [64]
    Luo B, Zhang S, Ma S, et al. Effects of cold air on cardiovascular disease risk factors in rat. Int J Environ Res Public Health, 2012; 9(7): 2312–2325. doi: 10.3390/ijerph9072312
    [65]
    Zhang X K, Zhang S Y, Wang C L, et al. Effects of moderate strength cold air exposure on blood pressure and biochemical indicators among cardiovascular and cerebrovascular patients. Int J Environ Res Public Health, 2014; 11(3): 2472–2487. doi: 10.3390/ijerph110302472
    [66]
    Greaney J L, Kenney W L, Alexander L M. Sympathetic function during whole body cooling is altered in hypertensive adults. Journal of Applied Physiology, 2017; 123(6): 1617–1624. doi: 10.1152/japplphysiol.00613.2017
    [67]
    Claeys M J, Rajagopalan S, Nawrot T S, et al. Climate and environmental triggers of acute myocardial infarction. Eur Heart J, 2017: 38(13): 955–960.
    [68]
    Okamoto-Mizuno K, Tsuzuki K, Mizuno K, et al. Effects of low ambient temperature on heart rate variability during sleep in humans. Eur J Appl Physiol, 2009; 105(2): 191–197. doi: 10.1007/s00421-008-0889-1
    [69]
    Thu Dang T A, Wraith D, Bambrick H, et al. Short - term effects of temperature on hospital admissions for acute myocardial infarction: A comparison between two neighboring climate zones in Vietnam. Environ Res, 2019;: 175: 167–177. doi: 10.1016/j.envres.2019.04.023
    [70]
    Lim Y H, Park M S, Kim Y, et al. Effects of cold and hot temperature on dehydration: a mechanism of cardiovascular burden. Int J Biometeorol, 2015; 59(8): 1035–1043. doi: 10.1007/s00484-014-0917-2
    [71]
    Li H, Yue P, Su Y, et al. Plasma levels of matrix metalloproteinase-9: A possible marker for cold-induced stroke risk in hypertensive rats. Neurosci Lett, 2019; 709: 134399. doi: 10.1016/j.neulet.2019.134399
    [72]
    Luo B, Zhang S Y, Ma S C, et al. Artificial cold air increases the cardiovascular risks in spontaneously hypertensive rats. Int J Environ Res Public Health, 2012; 9(9): 3197–3208. doi: 10.3390/ijerph9093197
    [73]
    Ebner A, Poitz D M, Alexiou K, et al. Secretion of adiponectin from mouse aorta and its role in cold storage-induced vascular dysfunction. Basic Res Cardiol, 2013; 108(6): 390. doi: 10.1007/s00395-013-0390-9
    [74]
    Crosswhite P, Chen K, Sun Z. AAV delivery of tumor necrosis factor-alpha short hairpin RNA attenuates cold-induced pulmonary hypertension and pulmonary arterial remodeling. Hypertension, 2014; 64(5): 1141–1150. doi: 10.1161/HYPERTENSIONAHA.114.03791
    [75]
    Yin K, Zhao L, Feng D, et al. Resveratrol attenuated low ambient temperature-induced myocardial hypertrophy via inhibiting cardiomyocyte apoptosis. Cell Physiol Biochem, 2015; 35(6): 2451–2462. doi: 10.1159/000374045
    [76]
    Dong M, Yang X, Lim S, et al. Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis. Cell Metab, 2013; 18(1): 118–129. doi: 10.1016/j.cmet.2013.06.003
    [77]
    Williams J W, Elvington A, Ivanov S, et al. Thermoneutrality but not UCP1 deficiency suppresses monocyte mobilization into blood. Circ Res, 2017; 121(6): 662–676. doi: 10.1161/CIRCRESAHA.117.311519
    [78]
    Xue Y, Yu X, Zhang X, et al. Protective effects of ginsenoside Rc against acute cold exposure-induced myocardial injury in rats. J Food Sci, 2021; 86(7): 3252–3264. doi: 10.1111/1750-3841.15757
    [79]
    Cong P, Liu Y, Liu N, et al. Cold exposure induced oxidative stress and apoptosis in the myocardium by inhibiting the Nrf2-Keap1 signaling pathway. BMC Cardiovasc Disord, 2018; 18(1): 36. doi: 10.1186/s12872-018-0748-x
    [80]
    Park J, Kim S, Kim D H, et al. Whole-body cold tolerance in older Korean female divers "haenyeo" during cold air exposure: effects of repetitive cold exposure and aging. Int J Biometeorol, 2018; 62(4): 543–551. doi: 10.1007/s00484-017-1463-5
    [81]
    Yin Z Q, Ding G B, Chen X, et al. Beclin1 haploinsufficiency rescues low ambient temperature-induced cardiac remodeling and contractile dysfunction through inhibition of ferroptosis and mitochondrial injury. Metabolism, 2020; 113: 154397. doi: 10.1016/j.metabol.2020.154397
    [82]
    Jiang S, Guo R, Zhang Y, et al. Heavy metal scavenger metallothionein mitigates deep hypothermia-induced myocardial contractile anomalies: role of autophagy. Am J Physiol Endocrinol Metab, 2013; 304(1): E74–86. doi: 10.1152/ajpendo.00176.2012
    [83]
    Zhang Y, Li L, Hua Y, et al. Cardiac-specific knockout of ET(A) receptor mitigates low ambient temperature-induced cardiac hypertrophy and contractile dysfunction. J Mol Cell Biol, 2012; 4(2): 97–107. doi: 10.1093/jmcb/mjs002
    [84]
    Zhang Y M, Hu N, Hua Y A, et al. Cardiac over expression of metallothionein rescues cold exposure-induced myocardial contractile dysfunction through attenuation of cardiac fibrosis despite cardiomyocyte mechanical anomalies. Free Radic Biol Med, 2012; 53(2): 194–207. doi: 10.1016/j.freeradbiomed.2012.04.005
    [85]
    Liang J, Yin K, Cao X, et al. Attenuation of low ambient temperature-induced myocardial hypertrophy by atorvastatin via promoting Bcl-2 expression. Cell Physiol Biochem, 2017; 41(1): 286–295. doi: 10.1159/000456111
    [86]
    Chen P G, Sun Z. AAV delivery of endothelin-1 shRNA attenuates cold-induced hypertension. Hum Gene Ther, 2017; 28(2): 190–199. doi: 10.1089/hum.2016.047
    [87]
    Luo Y, Zhang Y, Han X, et al. Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis. EbioMedicine, 2022; 82: 104087. doi: 10.1016/j.ebiom.2022.104087
    [88]
    Lu P, Xia G X, Zhao Q, et al. Temporal trends of the association between ambient temperature and hospitalisations for cardiovascular diseases in Queensland, Australia from 1995 to 2016: A time-stratified case-crossover study. Plos Medicine, 2020: 17(7): e1003176. doi: 10.1371/journal.pmed.1003176
    [89]
    Yang C Y, Meng X, Chen R J, et al. Long-term variations in the association between ambient temperature and daily cardiovascular mortality in Shanghai, China. Sci Total Environ, 2015; 538: 524–530. doi: 10.1016/j.scitotenv.2015.08.097
    [90]
    Martinez-Solanas E, Basagana X. Temporal changes in temperature-related mortality in Spain and effect of the implementation of a Heat Health Prevention Plan. Environ Res, 2019; 169: 102–113. doi: 10.1016/j.envres.2018.11.006
    [91]
    Hauton D, May S, Sabharwal R, et al. Cold-impaired cardiac performance in rats is only partially overcome by cold acclimation. J Exp Biol, 2011; 214(18): 3021–3031. doi: 10.1242/jeb.053587
    [92]
    Manolis A S, Manolis S A, Manolis A A, et al. Winter swimming: Body hardening and cardiorespiratory protection via sustainable acclimation. Curr Sports Med Rep, 2019; 18(11): 401–415. doi: 10.1249/JSR.0000000000000653
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