Submission systemSubmit
Advanced Search
Volume 2 Issue 2
Apr.  2022
Turn off MathJax
Article Contents
Article Navigation >  Frigid Zone Medicine  > 2022  >  2(2): 82-89
Jinxin Liu, Shaohong Fang, Shanjie Wang, Changbin Sun, Rong Sun, Hengxuan Cai, Bo Yu. Effects of intermittent cold-exposure on culprit plaque morphology in ST-segment elevation myocardial infarction patients: a retrospective study based on optical coherence tomography[J]. Frigid Zone Medicine, 2022, 2(2): 82-89. doi: 10.2478/fzm-2022-0011
Citation: Jinxin Liu, Shaohong Fang, Shanjie Wang, Changbin Sun, Rong Sun, Hengxuan Cai, Bo Yu. Effects of intermittent cold-exposure on culprit plaque morphology in ST-segment elevation myocardial infarction patients: a retrospective study based on optical coherence tomography[J]. Frigid Zone Medicine, 2022, 2(2): 82-89. doi: 10.2478/fzm-2022-0011
shu

Effects of intermittent cold-exposure on culprit plaque morphology in ST-segment elevation myocardial infarction patients: a retrospective study based on optical coherence tomography

doi: 10.2478/fzm-2022-0011
  • 1.

    Clinical Medicine College, Weifang Medical University, Weifang 261053, China

  • 2.

    Department of General Practice, Affiliated Hospital of Weifang Medical University, Weifang 261031, China

  • 3.

    Department of Cardiology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China

  • 4.

    The Key Laboratory of Myocardial Ischemia, Harbin Medical University, Ministry Education, Harbin 150086, China

More Information
  • Corresponding author: Jinxin Liu, E-mail: liujx_hmu@163.com; Bo Yu, E-mail: dryu_hmu@163.com
  • Received Date: 2021-08-21
  • Accepted Date: 2021-12-12
    • Available Online: 2022-04-30
    Abstract
  •   Objective  Present study aimed to explore the effects of intermittent cold-exposure (ICE) on culprit plaque morphology in patients with STsegment elevation myocardial infarction (STEMI) in frigid zone.  Methods  Totally 848 STEMI patients with plaque rupture (N = 637) or plaque erosion (N = 211) were enrolled consecutively according to optical coherence tomography imaging. Data on the changes of outdoor air temperature corresponding to 24 solar terms were collected. Patients were divided into different groups according to 24 solar terms and the number of days with indoor central heating. Imaging data were measured and analyzed qualitatively and quantitatively. Statistical analysis was conducted to elucidate the possible association of the STEMI patients of different groups with plaque morphology of culprit vessel with alterations of ambient temperature.  Results  The incidence of both plaque rupture and plaque erosion presented trough in summer. The incidence of plaque rupture reached a peak value in early winter when outdoor air temperature dropped below 0℃ and declined with supply of central heating. Persistent cold exposure in early winter was positively and significantly associated with plaque rupture. The incidence of plaque erosion presented a peak in severe winter with outdoor air temperature dropping below -20℃ and steady supply of central heating. ICE in severe winter was positively and significantly associated with plaque with intact intima, especially in aged male or current smoking patients. The positive correlation of cold exposure with lipid size in culprit plaque in winter weakened with central heating.  Conclusion  ICE resulted from switching staying in between outdoor cold environment and indoor warm temperature with central heating in severe winter changed culprit plaque morphology in STEMI. Plaque rupture decreased whereas plaque erosion increased impacted by ICE. The effect of ICE on the transformation of plaque morphology might be explained by reduced lipid deposition.

     

    • FullText(HTML)
  • loading
    • References(31)
  • [1]
    Jia H, Abtahian F, Aguirre A D, et al. In vivo diagnosis of plaque erosion and calcified nodule in patients with acute coronary syndrome by intravascular optical coherence tomography. J Am Coll Cardiol, 2013; 62(19): 1748-1758. doi: 10.1016/j.jacc.2013.05.071
    [2]
    Dai J, Xing L, Jia H, et al. In vivo predictors of plaque erosion in patients with st-segment elevation myocardial infarction: A clinical, angiographical, and intravascular optical coherence tomography study. Eur Heart J, 2018; 39(22): 2077-2085. doi: 10.1093/eurheartj/ehy101
    [3]
    Virmani R, Kolodgie F D, Burke A P, et al. Lessons from sudden coronary death: A comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler, Thromb, and Vasc biol, 2000; 20(5): 1262-1275. doi: 10.1161/01.ATV.20.5.1262
    [4]
    Jia H, Dai J, Hou J, et al. Effective anti-thrombotic therapy without stenting: Intravascular optical coherence tomography-based management in plaque erosion (the erosion study). Eur Heart J, 2017; 38(11): 792-800.
    [5]
    Niccoli G, Montone R A, Di Vito L, et al. Plaque rupture and intact fibrous cap assessed by optical coherence tomography portend different outcomes in patients with acute coronary syndrome. Eur Heart J, 2015; 36(22): 1377-1384. doi: 10.1093/eurheartj/ehv029
    [6]
    Yabushita H, Bouma B E, Houser S L, et al. Characterization of human atherosclerosis by optical coherence tomography. Circulation, 2002; 106(13): 1640-1645. doi: 10.1161/01.CIR.0000029927.92825.F6
    [7]
    Spencer F A, Goldberg R J, Becker R C, et al. Seasonal distribution of acute myocardial infarction in the second national registry of myocardial infarction. J Am Coll Cardiol, 1998; 31(6): 1226-1233. doi: 10.1016/S0735-1097(98)00098-9
    [8]
    Sun Z, Chen C, Xu D, et al. Effects of ambient temperature on myocardial infarction: A systematic review and meta-analysis. Environ Pollut, 2018; 241: 1106-1114. doi: 10.1016/j.envpol.2018.06.045
    [9]
    Sheth T, Nair C, Muller J, et al. Increased winter mortality from acute myocardial infarction and stroke: The effect of age. J Am Coll Cardiol, 1999; 33(7): 1916-1919 doi: 10.1016/S0735-1097(99)00137-0
    [10]
    Rumana N, Kita Y, Turin T C, et al. Seasonal pattern of incidence and case fatality of acute myocardial infarction in a japanese population (from the takashima ami registry, 1988 to 2003). Am J Cardiol, 2008; 102(10): 1307-1311. doi: 10.1016/j.amjcard.2008.07.005
    [11]
    Vasconcelos J, Freire E, Almendra R, et al. The impact of winter cold weather on acute myocardial infarctions in portugal. Environ Pollut, 2013; 183: 14-18. doi: 10.1016/j.envpol.2013.01.037
    [12]
    Ogbebor O, Odugbemi B, Maheswaran R, et al. Seasonal variation in mortality secondary to acute myocardial infarction in England and Wales: A secondary data analysis. BMJ Open, 2018; 8(7): e019242. doi: 10.1136/bmjopen-2017-019242
    [13]
    Davie G S, Baker M G, Hales S, et al. Trends and determinants of excess winter mortality in new zealand: 1980 to 2000. BMC Public Health, 2007; 7: 263. doi: 10.1186/1471-2458-7-263
    [14]
    Shibuya J, Kobayashi N, Asai K, et al. Comparison of coronary culprit lesion morphology determined by optical coherence tomography and relation to outcomes in patients diagnosed with acute coronary syndrome during winter -vs- other seasons. Am J Cardiol, 2019; 124(1): 31-38. doi: 10.1016/j.amjcard.2019.03.045
    [15]
    Prati F, Regar E, Mintz G S, et al. Expert review document on methodology, terminology, and clinical applications of optical coherence tomography: Physical principles, methodology of image acquisition, and clinical application for assessment of coronary arteries and atherosclerosis. Eur Heart J, 2010; 31(4): 401-415. doi: 10.1093/eurheartj/ehp433
    [16]
    Liu X, Sun C, Gu X, et al. Intraplaque neovascularization attenuated statin benefit on atherosclerotic plaque in cad patients: A follow-up study with combined imaging modalities. Atherosclerosis, 2019; 287: 134-139. doi: 10.1016/j.atherosclerosis.2019.06.912
    [17]
    Sher L. Effects of seasonal mood changes on seasonal variations in coronary heart disease: Role of immune system, infection, and inflammation. Med Hypotheses, 2001; 56(1): 104-106. doi: 10.1054/mehy.2000.1122
    [18]
    Keatinge W R, Coleshaw S R, Cotter F, et al. Increases in platelet and red cell counts, blood viscosity, and arterial pressure during mild surface cooling: Factors in mortality from coronary and cerebral thrombosis in winter. Br Med J, 1984; 289(6456): 1405-1408. doi: 10.1136/bmj.289.6456.1405
    [19]
    Chen X, Shang W, Huang X, et al. The effect of winter temperature on patients with ischemic stroke. Med Sci Monit, 2019; 25: 3839-3845. doi: 10.12659/MSM.916472
    [20]
    Mattila K J, Valtonen V V, Nieminen M S, et al. Role of infection as a risk factor for atherosclerosis, myocardial infarction, and stroke. Clin Infect Dis, 1998; 26(3): 719-734. doi: 10.1086/514570
    [21]
    Sun Z, Cade R, Morales C. Role of central angiotensin ii receptors in cold-induced hypertension. Am J Cardiol. 2002; 15(1 Pt 1): 85-92.
    [22]
    Barnett A G, Sans S, Salomaa V, et al. The effect of temperature on systolic blood pressure. Blood Press Monit, 2007; 12(3): 195-203. doi: 10.1097/MBP.0b013e3280b083f4
    [23]
    Cold exposure and winter mortality from ischaemic heart disease, cerebrovascular disease, respiratory disease, and all causes in warm and cold regions of europe. The eurowinter group. Lancet, 1997; 349(9062): 1341-1346. doi: 10.1016/S0140-6736(96)12338-2
    [24]
    Donaldson G C, Ermakov S P, Komarov Y M, et al. Cold related mortalities and protection against cold in yakutsk, eastern siberia: Observation and interview study. BMJ. 1998; 317(7164): 978-982. doi: 10.1136/bmj.317.7164.978
    [25]
    Liu J, Wang S, Hou J, et al. Proteomics profiling reveals insulinlike growth factor 1, collagen type vi alpha-2 chain, and fermitin family homolog 3 as potential biomarkers of plaque erosion in st-segment elevated myocardial infarction. Cir J, 2020; 84(6): 985-993. doi: 10.1253/circj.CJ-19-1206
    [26]
    Virmani R, Burke A P, Kolodgie F D, et al. Vulnerable plaque: The pathology of unstable coronary lesions. J Inter Card, 2002; 15(6): 439- 446. doi: 10.1111/j.1540-8183.2002.tb01087.x
    [27]
    Virmani R, Burke A P, Farb A, et al. Pathology of the vulnerable plaque. J Am Coll Cardiol, 2006; 47(Suppl 8): C13-18.
    [28]
    Tulenko T N, Sumner A E. The physiology of lipoproteins. Journal of Nuclear Cardiology, 2002; 9(6): 638-649. doi: 10.1067/mnc.2002.128959
    [29]
    Williams K J, Tabas I. The response-to-retention hypothesis of early atherogenesis. Arterioscler Thromb Vasc Biol, 1995; 15(5): 551-561. doi: 10.1161/01.ATV.15.5.551
    [30]
    McKie G L, Shamshoum H, Hunt K L, et al. Intermittent cold exposure improves glucose homeostasis despite exacerbating dietinduced obesity in mice housed at thermoneutrality. J Physiol, 2021; 600(4): 829-845.
    [31]
    Amano H, Noike R, Yabe T, et al. Frailty and coronary plaque characteristics on optical coherence tomography. Heart Vessels, 2020; 35(6): 750-761. doi: 10.1007/s00380-019-01547-2
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(5)  / Tables(1)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (420) PDF downloads(17) Cited by()
    Proportional views
    Related

    Contact Us

    Editorial Office: Frigid Zone Medicine, Editorial Office of Frigid Zone Medicine, Heilongjiang Health Development Research Center, Zhongshan Road 112, Xiangfang District, Harbin, 150036, China

    Tel: 0451-87253028

    E-mail: editorialoffice@frigidzonemedicine.com

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    Links

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return