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Unveiling metabolic flux changes during acute cold exposure

Pingping Tang Henghui Xu Yong Zhang

Pingping Tang, Henghui Xu, Yong Zhang. Unveiling metabolic flux changes during acute cold exposure[J]. Frigid Zone Medicine, 2023, 3(4): 193-195. doi: 10.2478/fzm-2023-0024
Citation: Pingping Tang, Henghui Xu, Yong Zhang. Unveiling metabolic flux changes during acute cold exposure[J]. Frigid Zone Medicine, 2023, 3(4): 193-195. doi: 10.2478/fzm-2023-0024

Unveiling metabolic flux changes during acute cold exposure

doi: 10.2478/fzm-2023-0024
More Information
  • [1] Bornstein M R, Neinast M D, Zeng X, et al. Comprehensive quantification of metabolic flux during acute cold stress in mice. Cell Metab, 2023; 35(11): 2077-2092. doi: 10.1016/j.cmet.2023.09.002
    [2] Jain R, Wade G, Ong I, et al. Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles. J Lipid Res, 2022; 63(7): 100197. doi: 10.1016/j.jlr.2022.100197
    [3] Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev, 2004; 84(1): 277-359. doi: 10.1152/physrev.00015.2003
    [4] Blondin D P, Frisch F, Phoenix S, et al. Inhibition of intracellular triglyceride lipolysis suppresses cold-induced brown adipose tissue metabolism and increases shivering in humans. Cell Metab, 2017; 25(2): 438-447. doi: 10.1016/j.cmet.2016.12.005
    [5] Rines A K, Sharabi K, Tavares C D, et al. Targeting hepatic glucose metabolism in the treatment of type 2 diabetes. Nat Rev Drug Discov, 2016; 15(11): 786-804. doi: 10.1038/nrd.2016.151
    [6] Nakagawa H, NAGAI K. Cold adaptation I. Effect of cold-exposure on gluconeogenesis. J Biol Chem, 1971; 69(5): 923-934.
    [7] Mukherji A, Bailey S M, Staels B, et al. The circadian clock and liver function in health and disease. J Hepatol, 2019; 71(1): 200-211. doi: 10.1016/j.jhep.2019.03.020
    [8] Yoneshiro T, Wang Q, Tajima K, et al. BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. Nature, 2019; 572(7771): 614-619. doi: 10.1038/s41586-019-1503-x
    [9] Ma Q X, Zhu W Y, Lu X C, et al. BCAA–BCKA axis regulates WAT browning through acetylation of PRDM16. Nature Metab, 2022; 4(1): 106-122. doi: 10.1038/s42255-021-00520-6
    [10] Puchalska P, Crawford P A. Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics. Cell Metab, 2017; 25(2): 262-284.
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出版历程
  • 收稿日期:  2023-11-27
  • 录用日期:  2023-11-27
  • 网络出版日期:  2024-01-29

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